Human FGF8 Protein
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产品编号
KMP3354
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别名
成纤维细胞生长因子 8, Human FGF8 Protein, FGF8
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规格
- 50ug
- 100ug
- 200ug
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- Human FGF8 Protein
产品介绍
| Alias | 成纤维细胞生长因子 8, Human FGF8 Protein, FGF8 |
| Catalog Number | KMP3354 |
| Product Description | The Human FGF8 Protein(KMP3354) is produced in E. coli. The target gene encoding the human FGF8a (NP_149355.1) (Gln23-Arg204) is expressed with an initial Met. |
| Molecular Name | FGF8 |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | 20mM Tris, 500mM NaCl, pH8.5 |
| Background | In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 21.3 kDa |
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