Human RNF43 Protein, His Tag
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产品编号
KMP3352
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别名
环指蛋白 43, Human RNF43 Protein, His Tag, RNF43
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规格
- 50ug
- 100ug
- 200ug
| Alias | 环指蛋白 43, Human RNF43 Protein, His Tag, RNF43 |
| Catalog Number | KMP3352 |
| Product Description | The Human RNF43 Protein(KMP3352) is produced in HEK293 Cells. The target gene encoding the human RNF43 (NP_060233.3) (Met1-Tyr197) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | RNF43 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 20.5 kDa |
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