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Human Allergin 1 Protein, His Tag

Human Allergin 1 Protein, His Tag

产品编号

KMP3346

别名

肥大细胞免疫球蛋白样受体, Human Allergin 1 Protein, His Tag, Allergin 1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肥大细胞免疫球蛋白样受体, Human Allergin 1 Protein, His Tag, Allergin 1
Catalog NumberKMP3346
Product DescriptionThe Human Allergin 1 Protein(KMP3346) is produced in HEK293 Cells. The target gene encoding the human MILR1 (NP_001078892.1) (Met1-Lys227) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameAllergin 1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundMILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to suppress immunoglobulin E (IgE)-mediated, mast cell-dependent responses in both mice and humans. The C allele of rs6504230 was associated with increased expression of MILR1, which was following the results of expression quantitative trait loci analysis using human leukocytes. The rs6504230 polymorphism affects MILR1 expression levels in humans, leading to a susceptibility to producing specific IgE antibodies against common allergens. Diseases associated with MILR1 include Mitochondrial Dna Depletion Syndrome 16 and Autosomal Dominant Progressive External Ophthalmoplegia.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight24.8 kDa

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