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Human NRG3 Protein, hFc Tag

Human NRG3 Protein, hFc Tag

产品编号

KMP3334

别名

神经调节蛋白3, Human NRG3 Protein, hFc Tag, NRG3

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias神经调节蛋白3, Human NRG3 Protein, hFc Tag, NRG3
Catalog NumberKMP3334
Product DescriptionThe Human NRG3 Protein(KMP3334) is produced in HEK293 Cells. The target gene encoding the human NRG3 (NP_001159444.1) (Glu282-Pro342) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameNRG3
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundNRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signaling through ERBB4. NRG3, a brain-enriched neurotrophin, undergoes alternative splicing and is implicated in several neurological disorders with developmental origins. It also promotes mammary differentiation during embryogenesis. NRG3 promotes early mammary morphogenesis and acts during specification of the mammary placode, an aggregate of epithelial cells that form during mid-embryogenesis. Diseases associated with NRG3 include Schizophrenia and Schizoaffective Disorder.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight33.7 kDa

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