Human NRG3 Protein, hFc Tag
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产品编号
KMP3334
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别名
神经调节蛋白3, Human NRG3 Protein, hFc Tag, NRG3
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规格
- 50ug
- 100ug
- 200ug
Alias | 神经调节蛋白3, Human NRG3 Protein, hFc Tag, NRG3 |
Catalog Number | KMP3334 |
Product Description | The Human NRG3 Protein(KMP3334) is produced in HEK293 Cells. The target gene encoding the human NRG3 (NP_001159444.1) (Glu282-Pro342) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | NRG3 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signaling through ERBB4. NRG3, a brain-enriched neurotrophin, undergoes alternative splicing and is implicated in several neurological disorders with developmental origins. It also promotes mammary differentiation during embryogenesis. NRG3 promotes early mammary morphogenesis and acts during specification of the mammary placode, an aggregate of epithelial cells that form during mid-embryogenesis. Diseases associated with NRG3 include Schizophrenia and Schizoaffective Disorder. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 33.7 kDa |