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Human FGF4 Protein

Human FGF4 Protein

产品编号

KMP3320

别名

成纤维细胞生长因子 4, Human FGF4 Protein, FGF4

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias成纤维细胞生长因子 4, Human FGF4 Protein, FGF4
Catalog NumberKMP3320
Product DescriptionThe Human FGF4 Protein(KMP3320) is produced in E. coli. The target gene encoding the human FGF4 (NP_001998.1) (Ser54-Leu206) is expressed.
Molecular NameFGF4
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH8.0
BackgroundFGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) and extracellular signal-related kinase 1/2 (ERK1/2). Fibroblast Growth Factor 4 (FGF-4) could not only increase the proliferation of bone marrow mesenchymal stem cells (BMSCs), but also induce BMSCs into hepatocyte-like cells in vitro. FGF4 transduced BMSCs contributed to liver regeneration might by the transplanted microenvironment. The FGF4-bFGF BMSCs thus can enhance the survival of the transplanted cells, diminish myocardial fibrosis, promote myocardial angiogenesis, and improve cardiac functions.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight16.8 kDa

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