Human CISD1 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CISD1 Protein, His Tag

Human CISD1 Protein, His Tag

产品编号

KMP3311

别名

重组人CDGSH铁硫域1, Human CISD1 Protein, His Tag, CISD1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	重组人CDGSH铁硫域1, Human CISD1 Protein, His Tag, CISD1
Catalog Number	KMP3311
Product Description	The Human CISD1 Protein(KMP3311) is produced in E. coli. The target gene encoding the human CISD1 (NP_060934.1) (Lys32-Thr108) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	CISD1
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 150mM NaCl, 10% Glycerol
Background	Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioenergetics, results in mitochondrial dysfunction and loss of striatal dopamine and tyrosine hydroxylase. CDGSH iron sulfur domain 1 (CISD1, also termed mitoNEET), an iron-containing outer mitochondrial membrane protein, negatively regulates ferroptotic cancer cell death. At the cellular level, CISD1 gene expression increased during human adipocyte differentiation in correlation with adipogenic genes.Thus it is a possible role of CISD1 in obesity-associated dysfunctional adipogenesis in human VAT.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	11.3 kDa

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