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Human LILRB1 Protein, hFc Tag

Human LILRB1 Protein, hFc Tag

产品编号

KMP3304

别名

白细胞免疫球蛋白样受体B1, Human LILRB1 Protein, hFc Tag, LILRB1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞免疫球蛋白样受体B1, Human LILRB1 Protein, hFc Tag, LILRB1
Catalog NumberKMP3304
Product DescriptionThe Human LILRB1 Protein(KMP3304) is produced in HEK293 Cells. The target gene encoding the human LILRB1 (ADJ55949.1) (Met1-His458) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameLILRB1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundLILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight73.9 kDa

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