Human LILRB1 Protein, hFc Tag
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产品编号
KMP3304
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别名
白细胞免疫球蛋白样受体B1, Human LILRB1 Protein, hFc Tag, LILRB1
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规格
- 50ug
- 100ug
- 200ug
Alias | 白细胞免疫球蛋白样受体B1, Human LILRB1 Protein, hFc Tag, LILRB1 |
Catalog Number | KMP3304 |
Product Description | The Human LILRB1 Protein(KMP3304) is produced in HEK293 Cells. The target gene encoding the human LILRB1 (ADJ55949.1) (Met1-His458) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | LILRB1 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 73.9 kDa |