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Human PSMA Protein, His Tag

Human PSMA Protein, His Tag

产品编号

KMP3292

别名

前列腺特异性膜抗原, Human PSMA Protein, His Tag, PSMA

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias前列腺特异性膜抗原, Human PSMA Protein, His Tag, PSMA
Catalog NumberKMP3292
Product DescriptionThe Human PSMA Protein(KMP3292) is produced in HEK293 Cells. The target gene encoding the human FOLH1 (NP_004467.1) (Lys44-Ala750) is expressed with a polyhistidine tag at the N-terminus. The purified protein is biotinylated in vitro.
Molecular NamePSMA
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundGlutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. FOLH1 is highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, brain (at protein level), and the capillary endothelium of a variety of tumors. FOLH1 has both folate hydrolase and N-acetylated alpha linked acidic dipeptidase (NAALADase) activity. It has a preference for tri-alpha-glutamate peptides. Genetic variation in FOLH1 may be associated with low folate levels and consequent hyperhomocysteinemia. This condition can result in increased risk of cardiovascular disease, neural tube defects, and cognitive deficits. FOLH1 also shows a promising role in directed imaging and therapy of recurrent or metastatic disease.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight81.7 kDa

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