Human MPZL3 Protein, His Tag_天津卡梅德科技发展有限公司

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Human MPZL3 Protein, His Tag

Human MPZL3 Protein, His Tag

产品编号

KMP3290

别名

髓磷脂蛋白零样 3, Human MPZL3 Protein, His Tag, MPZL3

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	髓磷脂蛋白零样 3, Human MPZL3 Protein, His Tag, MPZL3
Catalog Number	KMP3290
Product Description	The Human MPZL3 Protein(KMP3290) is produced in HEK293 Cells. The target gene encoding the human MPZL3 (NP_938016.1) (Met1-Ser158) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	MPZL3
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	MPZL3 (Myelin Protein Zero Like 3) is a Protein Coding gene. The encoded protein belongs to the myelin P0 protein family. MPZL3 is broadly expressed in skin, esophagus, and other tissues. MPZL3 was essential for normal differentiation, acting downstream of p63, ZNF750, KLF4, and RCOR1, each of which bound near the MPZL3 gene and controlled its expression. MPZL3 protein localized to mitochondria, where it interacted with FDXR, which was itself also found to be essential for differentiation. Together, MPZL3 and FDXR increased reactive oxygen species (ROS) to drive epidermal differentiation. ROS-induced differentiation is dependent upon the promotion of FDXR enzymatic activity by MPZL3. ROS induction by the MPZL3 and FDXR mitochondrial proteins is therefore essential for epidermal differentiation.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	15.6 kDa

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