Human ANTXR2 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human ANTXR2 Protein, hFc Tag

Human ANTXR2 Protein, hFc Tag

产品编号

KMP3284

别名

ANTXR 细胞粘附分子 2, Human ANTXR2 Protein, hFc Tag, ANTXR2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	ANTXR 细胞粘附分子 2, Human ANTXR2 Protein, hFc Tag, ANTXR2
Catalog Number	KMP3284
Product Description	The Human ANTXR2 Protein(KMP3284) is produced in HEK293 Cells. The target gene encoding the human ANTXR2 (NP_477520.2) (Met1-Asn317) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	ANTXR2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneous nodules, gingival hypertrophy and severe painful joint contracture. Anthrax toxin causes anthrax pathogenesis and expression levels of ANTXR2 (anthrax toxin receptor 2) are strongly correlated with anthrax toxin susceptibility. A recent genome-wide association study or GWAS identified that anthrax roxin receptor 2 (ANTXR2) was one of the risk loci for ankylosing spondylitis (AS). Previous study also showed that ANTXR2 could potentially affect new bone formation. This study aimed to investigate the possible mechanisms of ANTXR2 involved in AS pathogenesis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	57.4 kDa

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