Human LRRTM2 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human LRRTM2 Protein, hFc Tag

Human LRRTM2 Protein, hFc Tag

产品编号

KMP3273

别名

富亮氨酸重复跨膜神经元, Human LRRTM2 Protein, hFc Tag, LRRTM2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	富亮氨酸重复跨膜神经元, Human LRRTM2 Protein, hFc Tag, LRRTM2
Catalog Number	KMP3273
Product Description	The Human LRRTM2 Protein(KMP3273) is produced in HEK293 Cells. The target gene encoding the human LRRTM2 (NP_056379.1) (Met1-Arg422) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	LRRTM2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	LRRTM2 (Leucine-Rich Repeat Transmembrane Neuronal 2) is a Protein Coding gene. LRRTM2 belongs to the LRRTM family and is a key regulator of excitatory synapse development and function. It localizes to excitatory synapses in transfected hippocampal neurons, and shRNA-mediated knockdown of LRRTM2 leads to a decrease in excitatory synapses without affecting inhibitory synapses. LRRTM2 interacts with PSD-95 and regulates surface expression of AMPA receptors, and lentivirus-mediated knockdown of LRRTM2 in vivo decreases the strength of evoked excitatory synaptic currents. LRRTM2 induces only excitatory synapses, and that it also acts to induce synapses in transfected neurons similarly to neuroligin-1. Diseases associated with LRRTM2 include Tarp Syndrome and Histrionic Personality Disorder.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	71.2 kDa

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