Human Neurofascin Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human Neurofascin Protein, hFc Tag

Human Neurofascin Protein, hFc Tag

产品编号

KMP3272

别名

神经束蛋白, Human Neurofascin Protein, hFc Tag, Neurofascin

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	神经束蛋白, Human Neurofascin Protein, hFc Tag, Neurofascin
Catalog Number	KMP3272
Product Description	The Human Neurofascin Protein(KMP3272) is produced in HEK293 Cells. The target gene encoding the human NFASC (NP_001005388.2) (Met1-Gln939) is expressed with the Fc region of human IgG1 at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	Neurofascin
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton. It is broadly expressed in the brain, kidney, and other tissues. Diseases associated with NFASC include Neurodevelopmental Disorder With Central And Peripheral Motor Dysfunction and Demyelinating Polyneuropathy.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	130 kDa

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