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Human TNFSF9 Protein, Avi Tag, Fc Tag

Human TNFSF9 Protein, Avi Tag, Fc Tag

产品编号

KMP3271

别名

肿瘤坏死因子超家族成员 9, Human TNFSF9 Protein, Avi Tag, Fc Tag, TNFSF9

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子超家族成员 9, Human TNFSF9 Protein, Avi Tag, Fc Tag, TNFSF9
Catalog NumberKMP3271
Product DescriptionThe Human TNFSF9 Protein(KMP3271) is produced in HEK293 Cells. The target gene encoding the human TNFSF9 (NP_003802.1) (Arg71-Glu254) is expressed with a N-terminal Avi tag followed by a Fc region of human IgG1 tag. The purified protein is biotinylated in vitro.
Molecular NameTNFSF9
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
Background4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight47.98 kDa

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