Human MZB1 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human MZB1 Protein, hFc Tag

Human MZB1 Protein, hFc Tag

产品编号

KMP3269

别名

边缘区 B 和 B1 细胞特异性蛋白, Human MZB1 Protein, hFc Tag, MZB1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	边缘区 B 和 B1 细胞特异性蛋白, Human MZB1 Protein, hFc Tag, MZB1
Catalog Number	KMP3269
Product Description	The Human MZB1 Protein(KMP3269) is produced in HEK293 Cells. The target gene encoding the human MZB1 (NP_057543.2) (Met1-Thr185) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	MZB1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of gastric cancer (GC). Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	44.9 kDa

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