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Human NLGN4X Protein, hFc Tag

Human NLGN4X Protein, hFc Tag

产品编号

KMP3267

别名

神经胶质蛋白4X, Human NLGN4X Protein, hFc Tag, NLGN4X

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias神经胶质蛋白4X, Human NLGN4X Protein, hFc Tag, NLGN4X
Catalog NumberKMP3267
Product DescriptionThe Human NLGN4X Protein(KMP3267) is produced in HEK293 Cells. The target gene encoding the human NLGN4X (NP_065793.1) (Met1-Ser676) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameNLGN4X
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundNLGN4X (Neuroligin 4 X-Linked) is a Protein Coding gene. This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. NLGN4X interacts with discs large homolog 4 (DLG4). It is broadly expressed in the brain, ovary, and other tissues. Genetic mutations in NLGN4X, including point mutations and copy number variants (CNVs), have been associated with susceptibility to autism spectrum disorders (ASDs). Pathogenic mutations in the NLGN4X gene in ASDs and/or mental retardation (MR) are rare. Based on in vitro models, NLGN4X knockdown directly impacts the neurodevelopmental process during the formation of neurons and their connections.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight98.2 kDa

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