Human NLGN4X Protein, hFc Tag
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产品编号
KMP3267
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别名
神经胶质蛋白4X, Human NLGN4X Protein, hFc Tag, NLGN4X
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规格
- 50ug
- 100ug
- 200ug
Alias | 神经胶质蛋白4X, Human NLGN4X Protein, hFc Tag, NLGN4X |
Catalog Number | KMP3267 |
Product Description | The Human NLGN4X Protein(KMP3267) is produced in HEK293 Cells. The target gene encoding the human NLGN4X (NP_065793.1) (Met1-Ser676) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | NLGN4X |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | NLGN4X (Neuroligin 4 X-Linked) is a Protein Coding gene. This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. NLGN4X interacts with discs large homolog 4 (DLG4). It is broadly expressed in the brain, ovary, and other tissues. Genetic mutations in NLGN4X, including point mutations and copy number variants (CNVs), have been associated with susceptibility to autism spectrum disorders (ASDs). Pathogenic mutations in the NLGN4X gene in ASDs and/or mental retardation (MR) are rare. Based on in vitro models, NLGN4X knockdown directly impacts the neurodevelopmental process during the formation of neurons and their connections. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 98.2 kDa |