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Human GABARAP Protein, His Tag, MBP Tag

Human GABARAP Protein, His Tag, MBP Tag

产品编号

KMP3254

别名

GABA A 型受体相关蛋白, Human GABARAP Protein, His Tag, MBP Tag, GABARAP

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasGABA A 型受体相关蛋白, Human GABARAP Protein, His Tag, MBP Tag, GABARAP
Catalog NumberKMP3254
Product DescriptionThe Human GABARAP Protein(KMP3254) is produced in E. coli. The target gene encoding the human GABARAP (NP_009209.1) (Met1-Leu117) is expressed with an N-terminal polyhistidine-tagged MBP tag at the N-terminus.
Molecular NameGABARAP
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential for its plasma membrane localization.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight57.5 kDa

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