Human GABARAP Protein, His Tag, MBP Tag
-
产品编号
KMP3254
-
别名
GABA A 型受体相关蛋白, Human GABARAP Protein, His Tag, MBP Tag, GABARAP
-
规格
- 50ug
- 100ug
- 200ug
Alias | GABA A 型受体相关蛋白, Human GABARAP Protein, His Tag, MBP Tag, GABARAP |
Catalog Number | KMP3254 |
Product Description | The Human GABARAP Protein(KMP3254) is produced in E. coli. The target gene encoding the human GABARAP (NP_009209.1) (Met1-Leu117) is expressed with an N-terminal polyhistidine-tagged MBP tag at the N-terminus. |
Molecular Name | GABARAP |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential for its plasma membrane localization. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 57.5 kDa |