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Human PIG3 Protein, His Tag

Human PIG3 Protein, His Tag

产品编号

KMP3241

别名

肿瘤蛋白 p53 诱导蛋白 3, Human PIG3 Protein, His Tag, PIG3

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤蛋白 p53 诱导蛋白 3, Human PIG3 Protein, His Tag, PIG3
Catalog NumberKMP3241
Product DescriptionThe Human PIG3 Protein(KMP3241) is produced in E. coli. The target gene encoding the human TP53I3 (NP_004872.2) (Met1-Gln332) is expressed with a polyhistidine tag at the N-terminus.
Molecular NamePIG3
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundNutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of Nutlin-3.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight37.8 kDa

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