Human PIG3 Protein, His Tag
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产品编号
KMP3241
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别名
肿瘤蛋白 p53 诱导蛋白 3, Human PIG3 Protein, His Tag, PIG3
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规格
- 50ug
- 100ug
- 200ug
Alias | 肿瘤蛋白 p53 诱导蛋白 3, Human PIG3 Protein, His Tag, PIG3 |
Catalog Number | KMP3241 |
Product Description | The Human PIG3 Protein(KMP3241) is produced in E. coli. The target gene encoding the human TP53I3 (NP_004872.2) (Met1-Gln332) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | PIG3 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of Nutlin-3. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 37.8 kDa |