Human Endothelin B Receptor Protein, His Tag
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产品编号
KMP3235
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别名
B 型内皮素受体, Human Endothelin B Receptor Protein, His Tag, Endothelin B Receptor
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规格
- 50ug
- 100ug
- 200ug
| Alias | B 型内皮素受体, Human Endothelin B Receptor Protein, His Tag, Endothelin B Receptor |
| Catalog Number | KMP3235 |
| Product Description | The Human Endothelin B Receptor Protein(KMP3235) is produced in HEK293 Cells. The target gene encoding the human EDNRB (NP_000106.1) (Met1-Lys101) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | Endothelin B Receptor |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | The hypermethylation of EDNRB gene was remarkably related to infiltration and metastasis of gastric cancer and may attribute to the tumor progression. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. Low EDNRB expression played a role in the progression of ACC tumors. The autosomal recessive mutation in EDNRB may underlie a part of WS1 with the current diagnostic criteria, and supported that Hirschsprung's disease is a multifactorial genetic disease which requires additional factors. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 9.5 kDa |
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