Human Stathmin 1 Protein, His Tag
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产品编号
KMP3227
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别名
微管解聚蛋白 1, Human Stathmin 1 Protein, His Tag, Stathmin 1
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规格
- 50ug
- 100ug
- 200ug
Alias | 微管解聚蛋白 1, Human Stathmin 1 Protein, His Tag, Stathmin 1 |
Catalog Number | KMP3227 |
Product Description | The Human Stathmin 1 Protein(KMP3227) is produced in E. coli. The target gene encoding the human STMN1 (NP_005554.1) (Met1-Asp149) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | Stathmin 1 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and could be a novel therapeutic target in metastatic GC. STMN1 expression might serve as a biomarker for determining patient atypical meningioma prognosis. Stathmin1 (STMN1) is a cytosolic protein involved in microtubule dynamics through inhibition of tubulin polymerization and promotion of microtubule depolymerization, which has been implicated in carcinogenesis and aggressive behAvior in multiple epithelial malignancies. Stathmin 1 (STMN1) suppression was reported to reduce cellular viability and migration potential. STMN1 may be a promising candidate for targeted therapies in PDAC. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 19.5 kDa |