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Human Stathmin 1 Protein, His Tag

Human Stathmin 1 Protein, His Tag

产品编号

KMP3227

别名

微管解聚蛋白 1, Human Stathmin 1 Protein, His Tag, Stathmin 1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias微管解聚蛋白 1, Human Stathmin 1 Protein, His Tag, Stathmin 1
Catalog NumberKMP3227
Product DescriptionThe Human Stathmin 1 Protein(KMP3227) is produced in E. coli. The target gene encoding the human STMN1 (NP_005554.1) (Met1-Asp149) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameStathmin 1
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundStathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and could be a novel therapeutic target in metastatic GC. STMN1 expression might serve as a biomarker for determining patient atypical meningioma prognosis. Stathmin1 (STMN1) is a cytosolic protein involved in microtubule dynamics through inhibition of tubulin polymerization and promotion of microtubule depolymerization, which has been implicated in carcinogenesis and aggressive behAvior in multiple epithelial malignancies. Stathmin 1 (STMN1) suppression was reported to reduce cellular viability and migration potential. STMN1 may be a promising candidate for targeted therapies in PDAC.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight19.5 kDa

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