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Human THEM2 Protein, His Tag

Human THEM2 Protein, His Tag

产品编号

KMP3225

别名

酰基辅酶 A 硫酯酶 13, Human THEM2 Protein, His Tag, THEM2

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias酰基辅酶 A 硫酯酶 13, Human THEM2 Protein, His Tag, THEM2
Catalog NumberKMP3225
Product DescriptionThe Human THEM2 Protein(KMP3225) is produced in E. coli. The target gene encoding the human THEM2 (NP_060943.1) (Met1-Asn140) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameTHEM2
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation50mM Tris, 100mM Arg, pH8.0
BackgroundThe metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty acyl-CoAs, but their biological functions remain incompletely understood. Thioesterase superfamily member 2 (Them2; synonym Acot13) is enriched in oxidative tissues, associated with mitochondria, and relatively specific for long chain fatty acyl-CoA substrates. Using Them2(-/-) mice, we have demonstrated key roles for Them2 in regulating hepatic glucose and lipid metabolism. Members of the acyl-CoA thioesterase (Acot) gene family catalyze the hydrolysis of fatty acyl-CoAs, but their biological functions remain unknown. Thioesterase superfamily member 2 (Them2; synonym Acot13) is a broadly expressed mitochondria-associated Acot. Them2 was previously identified as an interacting protein of phosphatidylcholine transfer protein (PC-TP).
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight17.2 kDa

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