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Human CHRNB3 Protein, hFc Tag

Human CHRNB3 Protein, hFc Tag

产品编号

KMP3216

别名

胆碱能受体烟碱β3, Human CHRNB3 Protein, hFc Tag, CHRNB3

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias胆碱能受体烟碱β3, Human CHRNB3 Protein, hFc Tag, CHRNB3
Catalog NumberKMP3216
Product DescriptionThe Human CHRNB3 Protein(KMP3216) is produced in HEK293 Cells. The target gene encoding the human CHRNB3 (NP_000740.1) (Met1-Leu232) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameCHRNB3
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight51 kDa

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