Human PSG1 Protein, hFc Tag
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产品编号
KMP3214
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别名
P选择素糖蛋白配体1, Human PSG1 Protein, hFc Tag, PSG1
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规格
- 50ug
- 100ug
- 200ug
Alias | P选择素糖蛋白配体1, Human PSG1 Protein, hFc Tag, PSG1 |
Catalog Number | KMP3214 |
Product Description | The Human PSG1 Protein(KMP3214) is produced in HEK293 Cells. The target gene encoding the human PSG1 (NP_001171754.1) (Met1-Pro419) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | PSG1 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human and murine PSG family have been shown to induce anti-inflammatory cytokines from monocytes and macrophages and to stimulate angiogenesis. Two distinct domains of PSG1 are involved in the regulation of TGF-beta1 and provide a mechanistic framework for how PSGs modulate the immunoregulatory environment at the maternal-fetal interface for successful pregnancy outcome. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 70.2 kDa |