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Human PSG1 Protein, hFc Tag

Human PSG1 Protein, hFc Tag

产品编号

KMP3214

别名

P选择素糖蛋白配体1, Human PSG1 Protein, hFc Tag, PSG1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasP选择素糖蛋白配体1, Human PSG1 Protein, hFc Tag, PSG1
Catalog NumberKMP3214
Product DescriptionThe Human PSG1 Protein(KMP3214) is produced in HEK293 Cells. The target gene encoding the human PSG1 (NP_001171754.1) (Met1-Pro419) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NamePSG1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundPregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human and murine PSG family have been shown to induce anti-inflammatory cytokines from monocytes and macrophages and to stimulate angiogenesis. Two distinct domains of PSG1 are involved in the regulation of TGF-beta1 and provide a mechanistic framework for how PSGs modulate the immunoregulatory environment at the maternal-fetal interface for successful pregnancy outcome.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight70.2 kDa

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