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Human AKR1C4 Protein, His Tag

Human AKR1C4 Protein, His Tag

产品编号

KMP3201

别名

醛酮还原酶家族 1 成员 C4, Human AKR1C4 Protein, His Tag, AKR1C4

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias醛酮还原酶家族 1 成员 C4, Human AKR1C4 Protein, His Tag, AKR1C4
Catalog NumberKMP3201
Product DescriptionThe Human AKR1C4 Protein(KMP3201) is produced in E. coli. The target gene encoding the human AKR1C4 (AAH20744.1) (Met1-Tyr323) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameAKR1C4
SpeciesHuman
HostE. coli
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundAldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, and xenobiotic metabolism.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight39.4 kDa

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