| Alias | 醛酮还原酶家族 1 成员 C4, Human AKR1C4 Protein, His Tag, AKR1C4 |
| Catalog Number | KMP3201 |
| Product Description | The Human AKR1C4 Protein(KMP3201) is produced in E. coli. The target gene encoding the human AKR1C4 (AAH20744.1) (Met1-Tyr323) is expressed with a polyhistidine tag at the N-terminus. |
| Molecular Name | AKR1C4 |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug, 200ug |
| Purity | >85% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, and xenobiotic metabolism. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 39.4 kDa |
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