Human MSRB3 Protein, His Tag
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产品编号
KMP3190
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别名
重组人蛋氨酸亚克隆还原酶B3, Human MSRB3 Protein, His Tag, MSRB3
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规格
- 50ug
- 100ug
- 200ug
Alias | 重组人蛋氨酸亚克隆还原酶B3, Human MSRB3 Protein, His Tag, MSRB3 |
Catalog Number | KMP3190 |
Product Description | The Human MSRB3 Protein(KMP3190) is produced in HEK293 Cells. The target gene encoding the human MSRB3 (NP_001026849.1) (Gly26-Asp181) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | MSRB3 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | MSRB3 (Methionine Sulfoxide Reductase B3) is a Protein Coding gene. The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. This cysteine residue of MSRB3 is conserved in orthologs from yeast to humans and is involved in binding structural zinc. The affected individuals of six unrelated families were homozygous for the same transversion (c.265T>G) in MSRB3. In the inner ear, it is found in the sensory epithelium of the organ of Corti and vestibular end organs as well as in cells of the spiral ganglion. MSRB3-catalyzed reduction of methionine sulfoxides to methionine is essential for hearing. Diseases associated with MSRB3 include Deafness, Autosomal Recessive 74, and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 18.4 kDa |