Human MSRB3 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human MSRB3 Protein, hFc Tag

Human MSRB3 Protein, hFc Tag

产品编号

KMP3189

别名

重组人蛋氨酸亚克隆还原酶B3, Human MSRB3 Protein, hFc Tag, MSRB3

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	重组人蛋氨酸亚克隆还原酶B3, Human MSRB3 Protein, hFc Tag, MSRB3
Catalog Number	KMP3189
Product Description	The Human MSRB3 Protein(KMP3189) is produced in HEK293 Cells. The target gene encoding the human MSRB3 (NP_932346.1) (Gly26-Asp181) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	MSRB3
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	MSRB3 (Methionine Sulfoxide Reductase B3) is a Protein Coding gene. The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. This cysteine residue of MSRB3 is conserved in orthologs from yeast to humans and is involved in binding structural zinc. The affected individuals of six unrelated families were homozygous for the same transversion (c.265T>G) in MSRB3. In the inner ear, it is found in the sensory epithelium of the organ of Corti and vestibular end organs as well as in cells of the spiral ganglion. MSRB3-catalyzed reduction of methionine sulfoxides to methionine is essential for hearing. Diseases associated with MSRB3 include Deafness, Autosomal Recessive 74, and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	43.7 kDa

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