Human DEFB1 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human DEFB1 Protein, hFc Tag

Human DEFB1 Protein, hFc Tag

产品编号

KMP3188

别名

防御素β1, Human DEFB1 Protein, hFc Tag, DEFB1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	防御素β1, Human DEFB1 Protein, hFc Tag, DEFB1
Catalog Number	KMP3188
Product Description	The Human DEFB1 Protein(KMP3188) is produced in HEK293 Cells. The target gene encoding the human DEFB1 (NP_005209.1) (Met1-Lys68) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	DEFB1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. One such strategy is to reduce the production of the antimicrobial peptide beta-defensin 1 (DEFB1) by host epithelial cells. Beta-Defensin-1, an antimicrobial peptide encoded by the DEFB1 gene, is known to play an important role in lung mucosal immunity.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	31.8 kDa

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