Human PRND Protein, hFc Tag
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产品编号
KMP3187
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别名
朊病毒样蛋白双倍体, Human PRND Protein, hFc Tag, PRND
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规格
- 50ug
- 100ug
- 200ug
Alias | 朊病毒样蛋白双倍体, Human PRND Protein, hFc Tag, PRND |
Catalog Number | KMP3187 |
Product Description | The Human PRND Protein(KMP3187) is produced in HEK293 Cells. The target gene encoding the human PRND (NP_036541.2) (Met1-Gly152) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | PRND |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Doppel (PRND) is a paralogue of the mammalian prion (PRNP) gene. It is abundant in testis and, unlike PRNP, it is expressed at low levels in the adult central nervous system (CNS). Besides, doppel overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons. Prion-related protein doppel gene (PRND), as an essential member of the mammalian prion gene family, is associated with the scrapie susceptibility as well as phenotype traits, so the genetic variation of the PRND has been highly concerned recently, including the single nucleiotide polymorphism (SNP) and insertion/deletion (indel). |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 41.2 kDa |