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Human CD52 Protein, hFc Tag, Avi Tag

Human CD52 Protein, hFc Tag, Avi Tag

产品编号

KMP3185

别名

分化簇52, Human CD52 Protein, hFc Tag, Avi Tag, CD52

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias分化簇52, Human CD52 Protein, hFc Tag, Avi Tag, CD52
Catalog NumberKMP3185
Product DescriptionThe Human CD52 Protein(KMP3185) is produced in HEK293 Cells. The target gene encoding the human CD52 (NP_001794.2) (Met1-Ser36) is expressed with a C-terminal Fc region of human IgG1 tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular NameCD52
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight29.7 kDa

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