Human LIF Protein_天津卡梅德科技发展有限公司

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Human LIF Protein

Human LIF Protein

产品编号

KMP3171

别名

白血病抑制因子, Human LIF Protein, LIF

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白血病抑制因子, Human LIF Protein, LIF
Catalog Number	KMP3171
Product Description	The Human LIF Protein(KMP3171) is produced in HEK293 Cells. The target gene encoding the human LIF (P15018-1) (Met1-Phe202) is expressed.
Molecular Name	LIF
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<0.01 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone metabolism, cachexia, neural development, embryogenesis, and inflammation. LIF has potent proinflammatory properties, being the inducer of the acute phase protein synthesis and affecting cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that are capable to regulate the differentiation of embryonic stem cells, hematopoietic, and neuronal cells. LIF binds to the specific LIF receptor (LIFR-α) which forms a heterodimer with a specific subunit common to all members of that family of receptors, the GP130 signal-transducing subunit. This leads to the activation of the JAK/STAT and MAPK cascades. Due to its polyfunctional activities, LIF is involved in the pathogenic events and development of many diseases of various origins.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	19.7 kDa

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