Human PPT1 Protein, His Tag_天津卡梅德科技发展有限公司

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Human PPT1 Protein, His Tag

Human PPT1 Protein, His Tag

产品编号

KMP3163

别名

棕榈酰蛋白硫酯酶1, Human PPT1 Protein, His Tag, PPT1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	棕榈酰蛋白硫酯酶1, Human PPT1 Protein, His Tag, PPT1
Catalog Number	KMP3163
Product Description	The Human PPT1 Protein(KMP3163) is produced in HEK293 Cells. The target gene encoding the human PPT1 (P50897-1)(Met1-Gly306) is expressed with a C-terminal polyhistidine tag.
Molecular Name	PPT1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Mutations in the depalmitoylating enzyme gene, PPT1, cause the infantile form of Neuronal Ceroid Lipofuscinosis (NCL), an early onset neurodegenerative disease. Mutations in palmitoyl protein thioesterase-1 (PPT1) have been found to cause the infantile form of neuronal ceroid lipofuscinosis, which is a lysosomal storage disorder characterized by impaired degradation of fatty acid-modified proteins with accumulation of amorphous granular deposits in cortical neurons, leading to mental retardation and death. PPT1 catalyzes the cleavage of thioester linkages in S-acylated (palmitoylated) proteins and its deficiency leads to abnormal accumulation of thioesterified polypeptides (ceroid) in lysosomes causing INCL pathogenesis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	32.7 kDa

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