Human IL1RL2 Protein, hFc Tag
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产品编号
KMP3145
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别名
白细胞介素-36受体蛋白, Human IL1RL2 Protein, hFc Tag, IL1RL2
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规格
- 50ug
- 100ug
- 200ug
Alias | 白细胞介素-36受体蛋白, Human IL1RL2 Protein, hFc Tag, IL1RL2 |
Catalog Number | KMP3145 |
Product Description | The Human IL1RL2 Protein(KMP3145) is produced in HEK293 Cells. The target gene encoding the human IL1RL2 (NP_003845.2) (Met1-Tyr337) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | IL1RL2 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | IL1RL2 (Interleukin 1 Receptor-Like 2, also known as IL-36R) is a Protein Coding gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. This gene and four other interleukin 1 receptor family genes form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. The IL36 receptor is an important mediator molecule in the inflammatory response. Animal data suggest that IL1RL2 is involved in mucosal healing. Therapeutic intervention of IL-36R signaling offers an innovative treatment paradigm for targeting epithelial cell-mediated inflammatory diseases such as the life-threatening psoriasis variant called generalized pustular psoriasis (GPP). Diseases associated with IL1RL2 include Familial Cold Autoinflammatory Syndrome 2 and Geographic Tongue. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 63.2 kDa |