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Human IL1RL2 Protein, hFc Tag

Human IL1RL2 Protein, hFc Tag

产品编号

KMP3145

别名

白细胞介素-36受体蛋白, Human IL1RL2 Protein, hFc Tag, IL1RL2

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白细胞介素-36受体蛋白, Human IL1RL2 Protein, hFc Tag, IL1RL2
Catalog NumberKMP3145
Product DescriptionThe Human IL1RL2 Protein(KMP3145) is produced in HEK293 Cells. The target gene encoding the human IL1RL2 (NP_003845.2) (Met1-Tyr337) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameIL1RL2
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundIL1RL2 (Interleukin 1 Receptor-Like 2, also known as IL-36R) is a Protein Coding gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. This gene and four other interleukin 1 receptor family genes form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. The IL36 receptor is an important mediator molecule in the inflammatory response. Animal data suggest that IL1RL2 is involved in mucosal healing. Therapeutic intervention of IL-36R signaling offers an innovative treatment paradigm for targeting epithelial cell-mediated inflammatory diseases such as the life-threatening psoriasis variant called generalized pustular psoriasis (GPP). Diseases associated with IL1RL2 include Familial Cold Autoinflammatory Syndrome 2 and Geographic Tongue.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight63.2 kDa

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