Human LSP1 Protein, His Tag_天津卡梅德科技发展有限公司

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Human LSP1 Protein, His Tag

Human LSP1 Protein, His Tag

产品编号

KMP3139

别名

淋巴细胞特异性蛋白 1, Human LSP1 Protein, His Tag, LSP1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	淋巴细胞特异性蛋白 1, Human LSP1 Protein, His Tag, LSP1
Catalog Number	KMP3139
Product Description	The Human LSP1 Protein(KMP3139) is produced in HEK293 Cells. The target gene encoding the human LSP1 (AAH01785.1) (Met1-Pro339) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	LSP1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. LSP1 is a lymphocyte-specific intracellular Ca2(+)-binding protein. LSP1 localizes to nascent phagocytic cups during Fcgamma receptor-mediated phagocytosis, where it displays the same spatial and temporal distribution as the actin cytoskeleton. Down-regulation of LSP1 severely reduces the phagocytic activity of macrophages, clearly demonstrating a crucial role for this protein in Fcgamma receptor-mediated phagocytosis. LSP1, expressed in endothelial cells, plays a pivotal role in regulating subsequent recruitment steps following leukocyte adhesion.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	38.7 kDa

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