Human ILT4 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human ILT4 Protein, His Tag, Avi Tag

Human ILT4 Protein, His Tag, Avi Tag

产品编号

KMP3136

别名

白细胞免疫球蛋白样受体B2, Human ILT4 Protein, His Tag, Avi Tag, ILT4

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞免疫球蛋白样受体B2, Human ILT4 Protein, His Tag, Avi Tag, ILT4
Catalog Number	KMP3136
Product Description	The Human ILT4 Protein(KMP3136) is produced in HEK293 Cells. The target gene encoding the human LILRB2 (AAH36827.1) (Met1-Val461) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	ILT4
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 150mM NaCl, 0.02% Tween80, 10% Glycerol, pH8.5
Background	ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	51.06 kDa

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