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Human NKG2A Protein, His Tag

Human NKG2A Protein, His Tag

产品编号

KMP3119

别名

杀伤细胞凝集素样受体 C1, Human NKG2A Protein, His Tag, NKG2A

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias杀伤细胞凝集素样受体 C1, Human NKG2A Protein, His Tag, NKG2A
Catalog NumberKMP3119
Product DescriptionThe Human NKG2A Protein(KMP3119) is produced in HEK293 Cells. The target gene encoding the human KLRC1 (NP_002250.1) (Pro94-Leu233) is expressed with a polyhistidine tag at the N-terminus.
Molecular NameNKG2A
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundNKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this family are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NKG2 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight18.4 kDa

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