Human ESRP1 Protein, His Tag_天津卡梅德科技发展有限公司

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Human ESRP1 Protein, His Tag

Human ESRP1 Protein, His Tag

产品编号

KMP3100

别名

EH 结构域结合蛋白 1, Human ESRP1 Protein, His Tag, ESRP1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	EH 结构域结合蛋白 1, Human ESRP1 Protein, His Tag, ESRP1
Catalog Number	KMP3100
Product Description	The Human ESRP1 Protein(KMP3100) is produced in Insect Cells. The target gene encoding the human ESRP1 (NP_060167.2) (Met1-Ile681) is expressed with a polyhistidine tag at the N-terminus.
Molecular Name	ESRP1
Species	Human
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>65% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 300mM NaCl, 10% Glycerol, 0.5mM TCEP, pH7.5
Background	Epithelial splicing regulatory protein 1 (ESRP1) is an epithelial cell-specific RNA binding protein that controls several key cellular processes, like alternative splicing and translation. Epithelial splicing regulatory protein 1 (ESRP1) has been characterized as an essential splicing factor required for the regulation of human pluripotency and differentiation. ESRP1 regulates CD44 alternative splicing during the EMT process which plays an important role in EOC carcinogenesis. In addition, ESRP1 is associated with disease prognosis in epithelial ovarian cancer (EOC). Epithelial splicing regulatory protein 1 (ESRP1) and 2 (ESRP2), epithelial cell-specific regulators of alternative splicing, are downregulated during the epithelial-mesenchymal transition (EMT). There is a critical role of the AS regulator epithelial splicing regulator protein 1 (ESRP1) for intestinal homeostasis and pathogenesis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	77.9 kDa

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