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Human CYTL1 Protein, mFc Tag

Human CYTL1 Protein, mFc Tag

产品编号

KMP3095

别名

细胞因子样 1, Human CYTL1 Protein, mFc Tag, CYTL1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias细胞因子样 1, Human CYTL1 Protein, mFc Tag, CYTL1
Catalog NumberKMP3095
Product DescriptionThe Human CYTL1 Protein(KMP3095) is produced in HEK293 Cells. The target gene encoding the human CYTL1 (NP_061129.1) (Met1-Arg136) is expressed with the Fc region of mouse IgG1 at the C-terminus.
Molecular NameCYTL1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCytokine-like protein 1 (CYTL1) is a small widely expressed secreted protein lacking significant primary sequence homology to any other known protein. Cytokine-like 1 (CYTL1) is a novel potential cytokine that was first identified in CD34(+) cells derived from bone marrow and cord blood, and it was also found using our immunogenomics strategy. CYTL1 expression appears to be highest in the hematopoietic system and in chondrocytes; however, maintenance of cartilage in mouse models of arthritis is its only reported function in vivo. Despite lacking sequence homology to chemokines, CYTL1is predicted by computational methods to fold like a chemokine, and has been reported to function as a chemotactic agonist at the chemokine receptor CCR2 in mouse monocyte/macrophages. Recombinant CYTL1 promoted calcium flux in chondrocytes. Cytokine-like protein 1 (Cytl1), had been described as a protein expressed in CD34+ cells, and as a functional secreted protein involved in chondrogenesis and cartilage development.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight39.8 kDa

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