Human CYTL1 Protein, mFc Tag
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产品编号
KMP3095
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别名
细胞因子样 1, Human CYTL1 Protein, mFc Tag, CYTL1
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规格
- 50ug
- 100ug
- 200ug
Alias | 细胞因子样 1, Human CYTL1 Protein, mFc Tag, CYTL1 |
Catalog Number | KMP3095 |
Product Description | The Human CYTL1 Protein(KMP3095) is produced in HEK293 Cells. The target gene encoding the human CYTL1 (NP_061129.1) (Met1-Arg136) is expressed with the Fc region of mouse IgG1 at the C-terminus. |
Molecular Name | CYTL1 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Cytokine-like protein 1 (CYTL1) is a small widely expressed secreted protein lacking significant primary sequence homology to any other known protein. Cytokine-like 1 (CYTL1) is a novel potential cytokine that was first identified in CD34(+) cells derived from bone marrow and cord blood, and it was also found using our immunogenomics strategy. CYTL1 expression appears to be highest in the hematopoietic system and in chondrocytes; however, maintenance of cartilage in mouse models of arthritis is its only reported function in vivo. Despite lacking sequence homology to chemokines, CYTL1is predicted by computational methods to fold like a chemokine, and has been reported to function as a chemotactic agonist at the chemokine receptor CCR2 in mouse monocyte/macrophages. Recombinant CYTL1 promoted calcium flux in chondrocytes. Cytokine-like protein 1 (Cytl1), had been described as a protein expressed in CD34+ cells, and as a functional secreted protein involved in chondrogenesis and cartilage development. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 39.8 kDa |