Human GITR Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human GITR Protein, His Tag, Avi Tag

Human GITR Protein, His Tag, Avi Tag

产品编号

KMP3094

别名

糖皮质激素诱导的肿瘤坏死因子受体相关蛋白, Human GITR Protein, His Tag, Avi Tag, GITR

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	糖皮质激素诱导的肿瘤坏死因子受体相关蛋白, Human GITR Protein, His Tag, Avi Tag, GITR
Catalog Number	KMP3094
Product Description	The Human GITR Protein(KMP3094) is produced in HEK293 Cells. The target gene encoding the Human TNFRSF18 (NP_683700.1) (Met1-Glu161) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name	GITR
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	17.79 kDa

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