Human ABP1 Protein, His Tag_天津卡梅德科技发展有限公司

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Human ABP1 Protein, His Tag

Human ABP1 Protein, His Tag

产品编号

KMP3090

别名

含铜胺氧化酶 1, Human ABP1 Protein, His Tag, ABP1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	含铜胺氧化酶 1, Human ABP1 Protein, His Tag, ABP1
Catalog Number	KMP3090
Product Description	The Human ABP1 Protein(KMP3090) is produced in HEK293 Cells. The target gene encoding the human AOC1 (AAH14093.1) (Met1-Val751) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	ABP1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under control of the proximal AOC1 promoter was significantly enhanced by co-transfection of a WT1 expression construct. Binding of WT1 protein to a cis-regulatory element in the AOC1 promoter was confirmed by electrophoretic mobility shift assay and chromatin immunoprecipitation. WT1-dependent control of polyamine breakdown, which is mediated by changes in AOC1 expression, has a role in kidney organogenesis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	84.9 kDa

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