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Human Serum Amyloid P Protein, hFc Tag

Human Serum Amyloid P Protein, hFc Tag

产品编号

KMP3089

别名

血清淀粉样P蛋白, Human Serum Amyloid P Protein, hFc Tag, Serum Amyloid P

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias血清淀粉样P蛋白, Human Serum Amyloid P Protein, hFc Tag, Serum Amyloid P
Catalog NumberKMP3089
Product DescriptionThe Human Serum Amyloid P Protein(KMP3089) is produced in HEK293 Cells. The target gene encoding the Human APCS (P02743) (Met1-Val223) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameSerum Amyloid P
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, 10% Glycerol, 10% Trehalose, pH7.4
BackgroundSerum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight49.98 kDa

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