Human Serum Amyloid P Protein, hFc Tag
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产品编号
KMP3089
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别名
血清淀粉样P蛋白, Human Serum Amyloid P Protein, hFc Tag, Serum Amyloid P
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规格
- 50ug
- 100ug
- 200ug
Alias | 血清淀粉样P蛋白, Human Serum Amyloid P Protein, hFc Tag, Serum Amyloid P |
Catalog Number | KMP3089 |
Product Description | The Human Serum Amyloid P Protein(KMP3089) is produced in HEK293 Cells. The target gene encoding the Human APCS (P02743) (Met1-Val223) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | Serum Amyloid P |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, 10% Glycerol, 10% Trehalose, pH7.4 |
Background | Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 49.98 kDa |