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Human OGN Protein, His Tag

Human OGN Protein, His Tag

产品编号

KMP3071

别名

骨多糖, Human OGN Protein, His Tag, OGN

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias骨多糖, Human OGN Protein, His Tag, OGN
Catalog NumberKMP3071
Product DescriptionThe Human OGN Protein(KMP3071) is produced in HEK293 Cells. The target gene encoding the human OGN (NP_054776.1) (Met1-Phe298) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameOGN
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundOGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor-beta and may regulate osteoblast differentiation. OGN is broadly expressed in the gall bladder, endometrium, and other tissues. OGN reduced Zeb-1 expression via EGFR/Akt leading to inhibition of epithelial-mesenchymal transition. In vitro and in vivo, the OGN expression was demonstrated to reduce cell proliferation, inhibit invasion of colon cancer cells then impede cancer progression. Diseases associated with OGN include Inhibited Male Orgasm and Cornea Plana.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight33.2 kDa

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