Human UNC5A Protein, hFc Tag
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产品编号
KMP3064
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别名
净蛋白受体 UNC5A, Human UNC5A Protein, hFc Tag, UNC5A
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规格
- 50ug
- 100ug
- 200ug
Alias | 净蛋白受体 UNC5A, Human UNC5A Protein, hFc Tag, UNC5A |
Catalog Number | KMP3064 |
Product Description | The Human UNC5A Protein(KMP3064) is produced in HEK293 Cells. The target gene encoding the human UNC5A (NP_588610.2) (Met1-Tyr306) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | UNC5A |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 58.3 kDa |