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Human UNC5A Protein, hFc Tag

Human UNC5A Protein, hFc Tag

产品编号

KMP3064

别名

净蛋白受体 UNC5A, Human UNC5A Protein, hFc Tag, UNC5A

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias净蛋白受体 UNC5A, Human UNC5A Protein, hFc Tag, UNC5A
Catalog NumberKMP3064
Product DescriptionThe Human UNC5A Protein(KMP3064) is produced in HEK293 Cells. The target gene encoding the human UNC5A (NP_588610.2) (Met1-Tyr306) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NameUNC5A
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight58.3 kDa

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