Human Fc epsilon RI Protein_天津卡梅德科技发展有限公司

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Human Fc epsilon RI Protein

Human Fc epsilon RI Protein

产品编号

KMP3048

别名

高亲和力免疫球蛋白epsilon受体亚基α, Human Fc epsilon RI Protein, Fc epsilon RI

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	高亲和力免疫球蛋白epsilon受体亚基α, Human Fc epsilon RI Protein, Fc epsilon RI
Catalog Number	KMP3048
Product Description	The Human Fc epsilon RI Protein(KMP3048) is produced in HEK293 Cells. The target gene encoding the human FCER1A (NP_001992.1) (Met1-Gln205) is expressed.
Molecular Name	Fc epsilon RI
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. IgE receptor is comprised of an alpha subunit(FcERI), a beta subunit, and two gamma subunits. FcERI is glycosylated and contains 2 Ig-like (immunoglobulin-like) domains.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	21 kDa

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