Human Mesothelin Protein, His Tag
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产品编号
KMP3041
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别名
间皮素, Human Mesothelin Protein, His Tag, Mesothelin
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规格
- 50ug
- 100ug
- 200ug
Alias | 间皮素, Human Mesothelin Protein, His Tag, Mesothelin |
Catalog Number | KMP3041 |
Product Description | The Human Mesothelin Protein(KMP3041) is produced in HEK293 Cells. The target gene encoding the human MSLN (AAH09272.1) (Glu296-Gly580) is expressed with a polyHistide tag at the C-terminus. |
Molecular Name | Mesothelin |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 33.62 kDa |