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Human Mesothelin Protein, hFc Tag

Human Mesothelin Protein, hFc Tag

产品编号

KMP3040

别名

间皮素, Human Mesothelin Protein, hFc Tag, Mesothelin

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias间皮素, Human Mesothelin Protein, hFc Tag, Mesothelin
Catalog NumberKMP3040
Product DescriptionThe Human Mesothelin Protein(KMP3040) is produced in HEK293 Cells. The target gene encoding the human MSLN (Q13421-2) (Glu296-Gly580) is expressed with the fused Fc region of human IgG1 at the N-terminus. The expressed protein is biotinylated in vitro.
Molecular NameMesothelin
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>85% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight60.7 kDa

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