Human TNFSF4 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human TNFSF4 Protein, hFc Tag

Human TNFSF4 Protein, hFc Tag

产品编号

KMP3039

别名

肿瘤坏死因子超家族成员 4, Human TNFSF4 Protein, hFc Tag, TNFSF4

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子超家族成员 4, Human TNFSF4 Protein, hFc Tag, TNFSF4
Catalog Number	KMP3039
Product Description	The Human TNFSF4 Protein(KMP3039) is produced in HEK293 Cells. The target gene encoding the human TNFSF4 (Gln51-Leu183) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular Name	TNFSF4
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX40. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD4-stimulated B cells, this cytokine along with CD7 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	46.6 kDa

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