Human IGFBP7 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human IGFBP7 Protein, hFc Tag

Human IGFBP7 Protein, hFc Tag

产品编号

KMP3033

别名

胰岛素样生长因子结合蛋白 7, Human IGFBP7 Protein, hFc Tag, IGFBP7

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	胰岛素样生长因子结合蛋白 7, Human IGFBP7 Protein, hFc Tag, IGFBP7
Catalog Number	KMP3033
Product Description	The Human IGFBP7 Protein(KMP3033) is produced in HEK293 Cells. The target gene encoding the human IGFBP7 (Q16270) (Met 1-Leu 282) is fused with the Fc region of human IgG1 at the C-terminus.
Molecular Name	IGFBP7
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity, and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	53.5 kDa

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