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Human TSPAN1 Protein, mFc Tag

Human TSPAN1 Protein, mFc Tag

产品编号

KMP3030

别名

四跨膜蛋白 1, Human TSPAN1 Protein, mFc Tag, TSPAN1

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias四跨膜蛋白 1, Human TSPAN1 Protein, mFc Tag, TSPAN1
Catalog NumberKMP3030
Product DescriptionThe Human TSPAN1 Protein(KMP3030) is produced in HEK293 Cells. The target gene encoding the human TSPAN1 (NP_005718.2) (Tyr110-Asn211) is expressed with the Fc region of mouse IgG1 at the N-terminus.
Molecular NameTSPAN1
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-8 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone; in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight38.4 kDa

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