Human NFKBIB Protein, GST Tag_天津卡梅德科技发展有限公司

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Human NFKBIB Protein, GST Tag

Human NFKBIB Protein, GST Tag

产品编号

KMP3020

别名

NFKB 抑制因子 β, Human NFKBIB Protein, GST Tag, NFKBIB

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	NFKB 抑制因子 β, Human NFKBIB Protein, GST Tag, NFKBIB
Catalog Number	KMP3020
Product Description	The Human NFKBIB Protein(KMP3020) is produced in E. coli. The target gene encoding the human NFKBIB (NP_002494.2) (Met1-Val356) is expressed with an N-terminal GST tag.
Molecular Name	NFKBIB
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>75% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, 20% Glycerol, pH7.4
Background	NFKBIB (NFKB Inhibitor Beta) is a Protein Coding gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. NF-kappaB regulation involves the inhibitor protein NFKBIB, which form complexes with NF-kappaB to sequester it in the cytoplasm. Overexpression of NFKBIB protein in IAV infected cells led to lower levels of IAV. MiR-20a could promote activation of the NFkappaB pathway and downstream targets Livin and Survivin by targeting NFKBIB, which potentially contributed to GC chemoresistance.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	66.14 kDa

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