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Human CD47 Protein, His Tag

Human CD47 Protein, His Tag

产品编号

KMP3003

别名

整合素相关蛋白, Human CD47 Protein, His Tag, CD47

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias整合素相关蛋白, Human CD47 Protein, His Tag, CD47
Catalog NumberKMP3003
Product DescriptionThe Human CD47 Protein(KMP3003) is produced in HEK293 Cells. The target gene encoding the human CD47 (NP_942088.1) (Met1-Pro139) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameCD47
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight15.2 kDa

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