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Human ULBP2 Protein, His Tag, Avi Tag

Human ULBP2 Protein, His Tag, Avi Tag

产品编号

KMP2980

别名

重组人UL16结合蛋白2, Human ULBP2 Protein, His Tag, Avi Tag, ULBP2

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias重组人UL16结合蛋白2, Human ULBP2 Protein, His Tag, Avi Tag, ULBP2
Catalog NumberKMP2980
Product DescriptionThe Human ULBP2 Protein(KMP2980) is produced in HEK293 Cells. The target gene encoding the human ULBP2 (NP_079493.1) (Met1-Ser217) is expressed with a c-terminal polyhistidine tagged Avi tag at the C-terminus. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular NameULBP2
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundNKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight25 kDa

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